Isolation of an Antitumor Compound from Agaricus blazei Murill and Its Mechanism of Action
Author:
Affiliation:
1. Central Research Laboratory, School of Medicine, Ehime University, Shigenobu-cho, Onsen-gun, Ehime 791-0295, Japan
2. Second Department of Medical Biochemistry, Ehime University, Shigenobu-cho, Onsen-gun, Ehime 791-0295, Japan
Publisher
Oxford University Press (OUP)
Subject
Nutrition and Dietetics,Medicine (miscellaneous)
Link
http://academic.oup.com/jn/article-pdf/131/5/1409/24013871/4w050101409.pdf
Reference11 articles.
1. Antitumor activity and some properties of water-soluble polysaccharides from “Himematsutake,” the fruiting body of Agaricus blazei Murill;Mizuno;Agric. Biol. Chem.,1990
2. Inhibitory action of (1–6)-β-glucan-protein complex (FIII 020b) isolated from Agaricus blazei Murill (“Himematsutake”) on Meth A fibrosarcoma-bearing mice and its antitumor mechanism;Itoh;Jpn. J. Pharmacol.,1994
3. Formolysis of a potent antitumor (1–6)-β-glucan-protein complex from Agaricus blazei fruiting bodies and antitumor activity of the resulting products;Kawagishi;Carbohydr. Polym.,1990
4. Selective tumoricidal effect of soluble proteoglucan extracted from the Basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apotosis;Fujimiya;Cancer Immunol. Immunother.,1998
5. Antitumor promoting effect of an active component of polyporus ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A;Yazawa;Biol. Pharm. Bull.,2000
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