<i>Helicobacter pylori</i>and Inflammatory Bowel Disease: An Unresolved Enigma-Reference-Cited by-同舟云学术

Helicobacter pyloriand Inflammatory Bowel Disease: An Unresolved Enigma

Published:2022-12-14 Issue:3 Volume:29 Page:e5-e6
ISSN:1078-0998
Container-title:Inflammatory Bowel Diseases
language:en
Short-container-title:

Author:

Pokrotnieks Juris¹²^ORCID,Sitkin Stanislav³⁴⁵^ORCID

Affiliation:

1. Department of Internal Diseases, Rīga Stradiņš University , Riga , Latvia

2. Centre of Gastroenterology, Hepatology and Nutrition, Pauls Stradiņš Clinical University Hospital , Riga , Latvia

3. Department of Internal Diseases, Gastroenterology and Dietetics, North-Western State Medical University named after I.I. Mechnikov , St. Petersburg , Russia

4. Institute of Perinatology and Pediatrics, Almazov National Medical Research Centre , Saint Petersburg , Russia

5. R&D Department, Elpis Ltd , Riga , Latvia

Abstract

Lay SummaryThe article describes the hypothesis that there may be a noncausal relationship between Helicobacter pylori infection and inflammatory bowel disease (IBD) that is related to the host mucin glycan fucosylation status in the gastrointestinal tract. The proposed hypothesis may explain why IBD is less prevalent in patients with H. pylori, and no increased risk of IBD is seen after H. pylori eradication therapy, as was shown in the study by Tanner et al.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Link

https://academic.oup.com/ibdjournal/advance-article-pdf/doi/10.1093/ibd/izac248/47870153/izac248.pdf

Reference10 articles.

1. Inflammatory bowel disease and Helicobacter pylori: protective or present?;Tanner;Inflamm Bowel Dis.,2022

2. Effects of anti-Helicobacter pylori therapy on incidence of autoimmune diseases, including inflammatory bowel diseases;Lin;Clin Gastroenterol Hepatol.,2019

3. The relationship between Helicobacter pylori and inflammatory bowel disease;Zhong;Arch Iran Med.,2021

4. Helicobacter pylori eradication therapy is not associated with the onset of inflammatory bowel diseases. A case-control study;Rosania;J Gastrointestin Liver Dis.,2018

5. Seven days triple therapy for eradication of Helicobacter pylori does not alter the disease activity of patients with inflammatory bowel disease;Shinzaki;Intest Res,2018

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