IBD Flare in the COVID-19 Pandemic: Therapy Discontinuation Is to Blame

Author:

Bezzio Cristina1ORCID,Fiorino Gionata2ORCID,Ribaldone Davide G3,Armuzzi Alessandro45,Saibeni Simone1,Vernero Marta,Furfaro Federica,Pugliese Daniela,Manes Gianpiero,Pastorelli Luca,Gerardi Viviana,Viganò Chiara,Variola Angela,Caprioli Fabio,Zingone Fabiana,Scucchi Ludovica,Ardizzone Sandro,Baroni Stefania,Ricci Chiara,Onali Sara,Balestrieri Paola,Roselli Jenny,Bodini Giorgia,Daperno Marco,Lenti Marco,Baldoni Monia,Carparelli Sonia,Casini Valentina,Felice Carla,Cortelezzi Claudio,Amato Arnaldo,Mazzuoli Silvia,Coppini Francesca,Sartini Alessandro,Soriano Alessandra,Viscido Angelo,Buda Andrea,Grossi Laurino,Allocca Mariangela,Privitera Giuseppe,Armandi Angelo,

Affiliation:

1. Gastroenterology Unit, Rho Hospital, ASST Rhodense , Rho , Italy

2. Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele, University Vita-Salute San Raffaele , Milan , Italy

3. Division of Gastroenterology, Department of Medical Sciences, Università di Torino , Turin , Italy

4. IBD Unit, IRCCS Humanitas Research Hospital , Rozzano , Italy

5. Department of Biomedical Sciences, Humanitas University , Pieve Emanuele , Italy

Abstract

Lay Summary This prospective case-control study investigated the impact of severe acute respiratory syndrome coronavirus 2 infection on inflammatory bowel disease course and looked for risk factors associated with flares. In the severe acute respiratory syndrome coronavirus 2 pandemic era, inflammatory bowel disease course is not influenced by infection, while therapy discontinuation is a risk factor for disease flare.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Reference10 articles.

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2. Viral infections in inflammatory bowel disease: Tips and tricks for correct management;Craviotto;World J Gastroenterol.,2021

3. Review article: influenza A (H1N1) virus in patients with inflammatory bowel disease;Rahier;Aliment Pharmacol Ther.,2010

4. Adherence of infusible biologics during the time of COVID-19 among patients with inflammatory bowel disease: a nationwide Veterans Affairs cohort study;Khan;Gastroenterology,2020

5. COVID-19 and outcomes in patients with Inflammatory bowel disease: systematic review and meta-analysis;Tripathi;Inflamm Bowel Dis,2021

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