Tofacitinib for the Treatment of Pouch-Related Disorders: A Case Series-Reference-Cited by-同舟云学术

Tofacitinib for the Treatment of Pouch-Related Disorders: A Case Series

Published:2022-07-06 Issue:11 Volume:28 Page:1787-1789
ISSN:1078-0998
Container-title:Inflammatory Bowel Diseases
language:en
Short-container-title:

Author:

Dalal Rahul S¹^ORCID,Bains Kanwal²,Marcus Jenna¹,McClure Emma L¹,Allegretti Jessica R¹^ORCID

Affiliation:

1. Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School , Boston, MA , USA

2. Department of Nutrition, Brigham and Women’s Hospital, Harvard Medical School , Boston, MA , USA

Abstract

Lay Summary In this case series, 6 patients with chronic pouchitis (n = 3), cuffitis (n = 2), or Crohn’s-like disease of the pouch (n = 1) were treated with tofacitinib. One patient achieved clinical response; however, all patients ultimately discontinued therapy due to nonresponse or adverse events.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Link

https://academic.oup.com/ibdjournal/advance-article-pdf/doi/10.1093/ibd/izac147/44467841/izac147.pdf

Reference4 articles.

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2. A case of refractory chronic pouchitis successfully treated with tofacitinib;Okano;Clin J Gastroenterol.,2020

3. Tofacitinib in the treatment of Crohn’s-like disease of the pouch;Bauer;Am J Gastroenterol.,2020

4. Systematic review with meta-analysis: anti-TNF therapy in refractory pouchitis and crohn’s disease-like complications of the pouch after ileal pouch-anal anastomosis following colectomy for ulcerative colitis;Huguet;Inflamm Bowel Dis.,2018

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