Micafungin antifungal prophylaxis in children undergoing HSCT: can we give higher doses, less frequently? A pharmacokinetic study

Author:

Chandra Sharat12,Fukuda Tsuyoshi23,Mizuno Kana3,Davies Stella M12,Teusink-Cross Ashley4,Tarin Rich1,Marsh Rebecca A12,Vinks Alexander A23,Mehta Parinda A12

Affiliation:

1. Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

2. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA

3. Division of Clinical Pharmacology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

4. Division of Pharmacy, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

Funder

Astellas Pharma US

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference38 articles.

1. Risks, diagnosis and outcomes of invasive fungal infections in haematopoietic stem cell transplant recipients;Barnes;Br J Haematol,2007

2. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective;Tomblyn;Biol Blood Marrow Transplant,2009

3. Guideline for primary antifungal prophylaxis for pediatric patients with cancer or hematopoietic stem cell transplant recipients;Science;Pediatr Blood Cancer,2014

4. Invasive aspergillosis following hematopoietic cell transplantation: outcomes and prognostic factors associated with mortality;Upton;Clin Infect Dis,2007

5. Aspergillosis in children with cancer: a 34-year experience;Abbasi;Clin Infect Dis,1999

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