1. Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK
2. Linacre College, University of Oxford, Oxford, UK
3. Mathematical Institute, Andrew Wiles Building, University of Oxford, Oxford, UK
4. Psychiatry Department, Warneford Hospital, University of Oxford, Oxford, UK
5. Big Data Institute, University of Oxford, Oxford, UK
6. Medical Sciences Division, Nuffield Department of Population Health, University of Oxford, Oxford, UK
7. Department of Orthopaedics, Rheumatology and Musculoskeletal Medicine, Centre for Statistics in Medicine, University of Oxford, Oxford, UK