Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities

Author:

Coutzac Clélia12,Adam Julien34,Soularue Emilie125,Collins Michael25,Racine Antoine25,Mussini Charlotte6,Boselli Lisa1,Kamsukom Nyam7,Mateus Christine7,Charrier Mélinda12,Cassard Lydie1,Planchard David8,Ribrag Vincent9,Fizazi Karim210,Loriot Yohann10,Lepage Patricia11,Scoazec Jean-Yves234,Robert Caroline27,Carbonnel Franck25,Chaput Nathalie112

Affiliation:

1. Gustave Roussy, Laboratory d’Immunomonitoring en Oncologie, CNRS-UMS 3655 and INSERM-US23, Villejuif F-94805, France

2. University Paris-Sud, Faculté de Médecine, Le Kremlin Bicêtre, F-94276, France

3. Gustave Roussy, Department of Pathology and Laboratory Medicine [BIOpath], Villejuif F-94805, France

4. Gustave Roussy, AMMICa, CNRS-UMS 3655 and INSERM-US23, Villejuif F-94805, France

5. Department of Gastroenterology, Kremlin Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris [AP-HP], Le Kremlin Bicêtre, France

6. Department of Pathology, Kremlin Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris [AP-HP], Le Kremlin Bicêtre, France

7. Gustave Roussy, Département de Médecine, Service de Dermatologie, Villejuif, F-94805, France

8. Gustave Roussy, Département de Médecine Oncologique, Service de pathologie thoracique, Villejuif, F-94805, France

9. Gustave Roussy, Drug Development Department [DITEP] Villejuif F-94805, France

10. Gustave Roussy Cancer Campus [GRCC], Department of Cancer Medicine, Villejuif F-94805, France

11. Micalis Institute, INRA, AgroParisTech, University Paris-Saclay, 78350 Jouy-en-Josas, France

12. University Paris-Sud, Faculté de Pharmacie, Chatenay-Malabry, Châtenay-Malabry, F-92 296, France

Funder

Institut national de la santé et de la recherche médicale

Institut National du Cancer

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

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