ECCO Topical Review: Refractory Inflammatory Bowel Disease-Reference-Cited by-同舟云学术

ECCO Topical Review: Refractory Inflammatory Bowel Disease

Published:2021-06-23 Issue:10 Volume:15 Page:1605-1620
ISSN:1873-9946
Container-title:Journal of Crohn's and Colitis
language:en
Short-container-title:

Author:

Raine Tim¹,Verstockt Bram²³^ORCID,Kopylov Uri⁴⁵,Karmiris Konstantinos⁶,Goldberg Rimma⁷,Atreya Raja⁸,Burisch Johan⁹^ORCID,Burke John¹⁰,Ellul Pierre¹¹,Hedin Charlotte¹²¹³^ORCID,Holubar Stefan D¹⁴^ORCID,Katsanos Konstantinos¹⁵,Lobaton Triana¹⁶,Schmidt Carsten¹⁷,Cullen Garret¹⁸

Affiliation:

1. Department of Gastroenterology, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

2. Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium

3. Department of Chronic Diseases and Metabolism, TARGID - IBD, KU Leuven, Leuven, Belgium

4. Department of Gastroenterology, Sheba Medical Center, Ramat Gan, Israel

5. Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel

6. Department of Gastroenterology, Venizeleio General Hospital, Heraklion, Greece

7. Department of Gastroenterology, Monash Health and School of Clinical Sciences, Monash University, Melbourne, VIC, Australia

8. Department of Medicine 1, University of Erlangen-Nürnberg, Erlangen, Germany

9. Gastrounit, Medical Division, Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark

10. Colorectal and General Surgery, Beaumont Hospital, Dublin, Ireland

11. Department of Medicine, Division of Gastroenterology, Mater Dei Hospital, Msida, Malta

12. Karolinska Institutet, Department of Medicine Solna, Stockholm, Sweden

13. Karolinska University Hospital, Gastroenterology Unit, Department of Gastroenterology, Dermatovenereology and Rheumatology, Stockholm, Sweden

14. Department of Colon & Rectal Surgery, Cleveland Clinic, Cleveland, OH, USA

15. Department of Gastroenterology and Hepatology, University and Medical School of Ioannina, Ioannina, Greece

16. Department of Gastroenterology, Ghent University Hospital, Ghent, Belgium

17. Medical Faculty of the Friedrich Schiller University, Jena, Germany

18. Centre for Colorectal Disease, St Vincent’s University Hospital and School of Medicine, University College Dublin, Gastroenterology, Dublin, Ireland

Abstract

Abstract Inflammatory bowel disease is a chronic disease with variable degrees of extent, severity, and activity. A proportion of patients will have disease that is refractory to licensed therapies, resulting in significant impairment in quality of life. The treatment of these patients involves a systematic approach by the entire multidisciplinary team, with particular consideration given to medical options including unlicensed therapies, surgical interventions, and dietetic and psychological support. The purpose of this review is to guide clinicians through this process and provide an accurate summary of the available evidence for different strategies.

Funder

ECCO

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

Link

http://academic.oup.com/ecco-jcc/advance-article-pdf/doi/10.1093/ecco-jcc/jjab112/40352559/jjab112.pdf

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