Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis

Author:

Shinzaki Shinichiro1,Matsuoka Katsuyoshi2,Iijima Hideki1,Mizuno Shinta3,Serada Satoshi4,Fujimoto Minoru4,Arai Norimitsu5,Koyama Noriyuki5,Morii Eiichi6,Watanabe Mamoru2,Hibi Toshifumi7,Kanai Takanori3,Takehara Tetsuo1,Naka Tetsuji4

Affiliation:

1. Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan

2. Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan

3. Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

4. Laboratory of Immune Signal, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, Japan

5. Department of Research and Development, EIDIA Co. Ltd, Tokyo, Japan

6. Department of Pathology, Osaka University Graduate School of Medicine, Osaka, Japan

7. Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan

Funder

Japan Agency for Medical Research and Development

Eidia Co. Ltd

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

Reference30 articles.

1. Mucosal healing in inflammatory bowel diseases: a systematic review;Neurath;Gut,2012

2. Clinical implications of mucosal healing for the management of IBD;Pineton de Chambrun;Nat Rev Gastroenterol Hepatol,2010

3. Regulation of the human C-reactive protein gene, a major marker of inflammation and cancer;Toniatti;Mol Biol Med,1990

4. C-reactive protein as a marker for inflammatory bowel disease;Vermeire;Inflamm Bowel Dis,2004

5. Relationships between disease activity and serum and fecal biomarkers in patients with Crohn’s disease;Jones;Clin Gastroenterol Hepatol,2008

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