Targeting Endothelial Ligands: ICAM-1/alicaforsen, MAdCAM-1

Author:

Reinisch Walter1,Hung Kenneth2,Hassan-Zahraee Mina3,Cataldi Fabio4

Affiliation:

1. Department of Internal Medicine III, Division of Gastroenterology & Hepatology, Medical University of Vienna, Vienna, Austria

2. Pfizer Inc, Precision Medicine, Cambridge, MA, USA

3. Early Clinical R&D | Precision Medicine, Pfizer Inc, Cambridge, MA, USA

4. Cataldi Research Solutions, Beverly, MA, USA

Funder

F. Hoffmann-La Roche Ltd

Takeda Development Center Americas, Inc

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,General Medicine

Reference76 articles.

1. Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1);Dustin;J Immunol,1986

2. Interactions between epithelial cells and T lymphocytes: role of adhesion molecules;Singer;J Leukoc Biol,1990

3. Regional differences in constitutive and induced ICAM-1 expression in vivo;Panés;Am J Physiol,1995

4. Cytokine-induced VCAM-1 and ICAM-1 expression in different organs of the mouse;Henninger;J Immunol,1997

5. Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohn’s ileocolitis;Baert;Gastroenterology,1999

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