Magnetic Resonance Enterography and Intestinal Ultrasound for the Assessment and Monitoring of Crohn’s Disease

Author:

Kumar Shankar1ORCID,De Kock Isabelle2,Blad William3,Hare Richard4,Pollok Richard5,Taylor Stuart A1

Affiliation:

1. Centre for Medical Imaging, University College London , London , UK

2. Radiology Department, Ghent University Hospital , Ghent , Belgium

3. Department of Gastroenterology, University College Hospitals NHS Foundation Trust , London , UK

4. Faculty of Biology, Medicine and Health, University of Manchester , Manchester , UK

5. Department of Gastroenterology, St George’s University Hospitals NHS Foundation Trust , London , UK

Abstract

Abstract Magnetic resonance enterography [MRE] and intestinal ultrasound [IUS] have developed rapidly in the past few decades, emerging as the primary non-invasive options for both diagnosing and monitoring Crohn’s disease [CD]. In this review, we evaluate the pertinent data relating to the use of MRE and IUS in CD. We summarise the key imaging features of CD activity, highlight their increasing role in both the clinical and the research settings, and discuss how these modalities fit within the diagnostic pathway. We discuss how they can be used to assess disease activity and treatment responsiveness, including the emergence of activity scores for standardised reporting. Additionally, we address areas of controversy such as the use of contrast agents, the role of diffusion-weighted imaging, and point-of-care ultrasound. We also highlight exciting new developments, including the applications of artificial intelligence. Finally, we provide suggestions for future research priorities.

Publisher

Oxford University Press (OUP)

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