The 2023 Impact of Inflammatory Bowel Disease in Canada: Direct Health System and Medication Costs

Author:

Kuenzig M Ellen12ORCID,Coward Stephanie3ORCID,Targownik Laura E4ORCID,Murthy Sanjay K56,Benchimol Eric I12789ORCID,Windsor Joseph W3,Bernstein Charles N1011ORCID,Bitton Alain12,Jones Jennifer L13,Lee Kate14,Peña-Sánchez Juan-Nicolás15ORCID,Rohatinsky Noelle16ORCID,Ghandeharian Sara14,Im James H B12,Jogendran Rohit17,Meka Saketh18,Weinstein Jake12,Jones May Tyrel19,Jogendran Manisha20,Tabatabavakili Sahar21,Hazan Elias22,Hu Malini17,Osei Jessica Amankwah15,Khan Rabia127,Wang Grace17ORCID,Browne Mira12,Davis Tal12,Goddard Quinn3,Gorospe Julia3,Latos Kate14,Mason Kate14,Kerr Jack23,Balche Naji13,Sklar Anna13,Kaplan Gilaad G3ORCID

Affiliation:

1. SickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children , Toronto, Ontario , Canada

2. Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children , Toronto, Ontario , Canada

3. Departments of Medicine and Community Health Sciences, University of Calgary , Calgary, Alberta , Canada

4. Division of Gastroenterology and Hepatology, Mount Sinai Hospital, University of Toronto , Toronto, Ontario , Canada

5. Department of Medicine, University of Ottawa , Ottawa, Ontario , Canada

6. The Ottawa Hospital IBD Centre , Ottawa, Ontario , Canada

7. ICES , Toronto, Ontario , Canada

8. Department of Paediatrics, Temerty Faculty of Medicine, University of Toronto , Toronto, Ontario , Canada

9. Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health, University of Toronto , Toronto, Ontario , Canada

10. Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba , Winnipeg, Manitoba , Canada

11. University of Manitoba IBD Clinical and Research Centre , Winnipeg, Manitoba , Canada

12. Division of Gastroenterology and Hepatology, McGill University Health Centre IBD Centre, McGill University , Montréal, Quebec , Canada

13. Departments of Medicine, Clinical Health, and Epidemiology, Dalhousie University , Halifax , Nova Scotia , Canada

14. Crohn’s and Colitis Canada , Toronto, Ontario , Canada

15. Department of Community Health and Epidemiology, University of Saskatchewan , Saskatoon , Saskatchewan , Canada

16. College of Nursing, University of Saskatchewan , Saskatoon , Saskatchewan , Canada

17. Department of Medicine, University of Toronto , Toronto, Ontario , Canada

18. Department of Neuroscience, McGill University , Montreal, Quebec , Canada

19. Division of Gastroenterology and Hepatology, University Health Network, University of Toronto , Toronto, Ontario , Canada

20. Department of Medicine, Queen’s University , Kingston, Ontario , Canada

21. Department of Gastroenterology, University of Toronto , Toronto, Ontario , Canada

22. Department of Internal Medicine, University of Toronto , Toronto, Ontario , Canada

23. Department of Medicine, Memorial University of Newfoundland , St John’s Newfoundland , Canada

Abstract

Abstract Healthcare utilization among people living with inflammatory bowel disease (IBD) in Canada has shifted from inpatient management to outpatient management; fewer people with IBD are admitted to hospitals or undergo surgery, but outpatient visits have become more frequent. Although the frequency of emergency department (ED) visits among adults and seniors with IBD decreased, the frequency of ED visits among children with IBD increased. Additionally, there is variation in the utilization of IBD health services within and between provinces and across ethnocultural and sociodemographic groups. For example, First Nations individuals with IBD are more likely to be hospitalized than the general IBD population. South Asian children with Crohn’s disease are hospitalized more often than their Caucasian peers at diagnosis, but not during follow-up. Immigrants to Canada who develop IBD have higher health services utilization, but a lower risk of surgery compared to individuals born in Canada. The total direct healthcare costs of IBD, including the cost of hospitalizations, ED visits, outpatient visits, endoscopy, cross-sectional imaging, and medications are rising rapidly. The direct health system and medication costs of IBD in Canada are estimated to be $3.33 billion in 2023, potentially ranging from $2.19 billion to $4.47 billion. This is an increase from an estimated $1.28 billion in 2018, likely due to sharp increases in the use of biologic therapy over the past two decades. In 2017, 50% of total direct healthcare costs can be attributed to biologic therapies; the proportion of total direct healthcare costs attributed to biologic therapies today is likely even greater.

Funder

AbbVie Corporation

Janssen Canada

Pfizer Canada

Bristol-Myers Squibb Canada

Amgen Canada

Takeda Foundation

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical)

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