Characterization of the impact of rpoB mutations on the in vitro and in vivo competitive fitness of Clostridium difficile and susceptibility to fidaxomicin-Reference-Cited by-同舟云学术

Characterization of the impact of rpoB mutations on the in vitro and in vivo competitive fitness of Clostridium difficile and susceptibility to fidaxomicin

Published:2017-12-15 Issue:4 Volume:73 Page:973-980
ISSN:0305-7453
Container-title:Journal of Antimicrobial Chemotherapy
language:en
Short-container-title:

Author:

Kuehne Sarah A¹²³,Dempster Andrew W¹,Collery Mark M¹,Joshi Nimitray¹,Jowett Jamie¹,Kelly Michelle L¹,Cave Rory¹,Longshaw Chris M⁴,Minton Nigel P¹²^ORCID

Affiliation:

1. Clostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), School of Life Sciences, University of Nottingham, Nottingham, UK

2. Gastrointestinal and Liver Disorders Theme of the NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK

3. School of Dentistry, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

4. Astellas Pharma Europe Ltd, Chertsey, UK

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Link

http://academic.oup.com/jac/article-pdf/73/4/973/25087835/dkx486.pdf

Reference33 articles.

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2. Reconsidering the sporulation characteristics of hypervirulent Clostridium difficile BI/NAP1/027;Burns;PLoS One,2011

3. Best strategies in recurrent or persistent Clostridium difficile infection;Cocanour;Surg Infect (Larchmt),2011