Development of a Multiresidue Method for Endocrine-Disrupting Pesticides by Solid Phase Extraction and Determination by UHPLC-MS/MS from Drinking Water Samples

Author:

Liu Shaoying1,Huang Xihui1,Hu Kejun1,Jin Quan1,Zhu Guonian2

Affiliation:

1. Laboratory of Chemistry and Physics, Hangzhou Center for Disease Control and Prevention, Hangzhou, P.R. China

2. Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, P.R. China

Abstract

Abstract A rapid and efficient method based on solid phase extraction and liquid chromatography–tandem mass spectrometry was validated, allowing the determination of the endocrine-disrupting herbicides (acetochlor, alachlor, amitrole and atrazine), fungicides (carbendazim, triadimefon, penconazole and propiconazole), and insecticides (carbaryl and carbofuran) in drinking water. Low method detection limits (0.01–0.64 ng/L) and method quantification limits (0.03–2.13 ng/L) were obtained with satisfactory recoveries and precision for the endocrine-disrupting pesticides. The method was applied for real drinking water samples collected in the area of the city of Hangzhou (Zhejiang, China); the results showed that carbendazim, atrazine and acetochlor were detected in the drinking water samples and acetochlor was the most detected analyte.

Funder

Zhejiang Medical Technology and Education

Publisher

Oxford University Press (OUP)

Subject

General Medicine,Analytical Chemistry

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