Regional and global contributions of air pollution to risk of death from COVID-19

Author:

Pozzer Andrea12ORCID,Dominici Francesca3,Haines Andy4,Witt Christian5ORCID,Münzel Thomas67ORCID,Lelieveld Jos28ORCID

Affiliation:

1. International Center for Theoretical Physics, Trieste, Italy

2. Ma x Planck Institute for Chemistry, Atmospheric Chemistry Department, Mainz, Germany

3. Harvard T.H. Chan School of Public Health, Department of Biostatistics, Boston, MA, USA

4. Centre for Climate Change and Planetary Health, London School of Hygiene and Tropical Medicine, London, UK

5. Charité University Medicine, Pneumological Oncology and Transplantology, Berlin, Germany

6. University Medical Center of the Johannes Gutenberg University, Mainz, Germany

7. German Center for Cardiovascular Research, Mainz, Germany

8. The Cyprus Institute, Climate and Atmosphere Research Center, Nicosia, Cyprus

Abstract

Abstract Aims The risk of mortality from the coronavirus disease that emerged in 2019 (COVID-19) is increased by comorbidity from cardiovascular and pulmonary diseases. Air pollution also causes excess mortality from these conditions. Analysis of the first severe acute respiratory syndrome coronavirus (SARS-CoV-1) outcomes in 2003, and preliminary investigations of those for SARS-CoV-2 since 2019, provide evidence that the incidence and severity are related to ambient air pollution. We estimated the fraction of COVID-19 mortality that is attributable to the long-term exposure to ambient fine particulate air pollution. Methods and results We characterized global exposure to fine particulates based on satellite data, and calculated the anthropogenic fraction with an atmospheric chemistry model. The degree to which air pollution influences COVID-19 mortality was derived from epidemiological data in the USA and China. We estimate that particulate air pollution contributed ∼15% (95% confidence interval 7–33%) to COVID-19 mortality worldwide, 27% (13 – 46%) in East Asia, 19% (8–41%) in Europe, and 17% (6–39%) in North America. Globally, ∼50–60% of the attributable, anthropogenic fraction is related to fossil fuel use, up to 70–80% in Europe, West Asia, and North America. Conclusion Our results suggest that air pollution is an important cofactor increasing the risk of mortality from COVID-19. This provides extra motivation for combining ambitious policies to reduce air pollution with measures to control the transmission of COVID-19.

Funder

DZHK

German Center for Cardiovascular Research

Partner Site Rhine-Main

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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