Mapping SCORing of Atopic Dermatitis (SCORAD) and objective SCORAD to the Eczema Area and Severity Index to facilitate large-scale meta-analyses of molecular data-Reference-Cited by-同舟云学术

Mapping SCORing of Atopic Dermatitis (SCORAD) and objective SCORAD to the Eczema Area and Severity Index to facilitate large-scale meta-analyses of molecular data

Published:2024-05-31 Issue: Volume: Page:
ISSN:0007-0963
Container-title:British Journal of Dermatology
language:en
Short-container-title:

Author:

Hübenthal Matthias¹^ORCID,Dai Chengliang²^ORCID,Brown Sara J³^ORCID,Heinrich Luise⁴^ORCID,Kind Barbara⁴^ORCID,Harder Inken¹^ORCID,Schmitt Jochen⁴^ORCID,Werfel Thomas⁵^ORCID,Weidinger Stephan¹⁶^ORCID

Affiliation:

1. Department of Dermatology, Quincke Research Center, University Hospital Schleswig-Holstein , Campus Kiel, Kiel , Germany

2. UCB S.A. , London , UK

3. Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh , Edinburgh , UK

4. Center for Evidence-Based Healthcare, University Hospital Carl Gustav Carus and Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden , Dresden , Germany

5. Department of Dermatology and Allergy, Hannover Medical School , Hannover , Germany

6. Center for Inflammatory Skin Diseases, Department of Dermatology and Allergy, University Hospital Schleswig-Holstein , Campus Kiel, Kiel , Germany

Abstract

We used data from 1501 patients to build mathematical models for mapping between common measures of atopic dermatitis severity, including SCORing of Atopic Dermatitis (SCORAD), objective SCORAD (oSORAD) and the Eczema Area and Severity Index (EASI). These models can be used to facilitate progress in harmonizing patient data across studies, enabling important comparative analyses at scale.

Funder

European Federation of Pharmaceutical Industries and Associations

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/bjd/advance-article-pdf/doi/10.1093/bjd/ljae232/58665484/ljae232.pdf

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