High intratumoral 5-hydroxymethylcytosine levels protect against disease relapse in patients with atypical fibroxanthoma and pleomorphic dermal sarcoma-Reference-Cited by-同舟云学术

High intratumoral 5-hydroxymethylcytosine levels protect against disease relapse in patients with atypical fibroxanthoma and pleomorphic dermal sarcoma

Published:2024-04-26 Issue:2 Volume:191 Page:295-296
ISSN:0007-0963
Container-title:British Journal of Dermatology
language:en
Short-container-title:

Author:

Gambichler Thilo¹²³^ORCID,Razeghpour Fahimeh¹,Sorescu Emilia¹,Stücker Markus¹,Abu Rached Nessr¹,Becker Jürgen C⁴⁵,Susok Laura¹³

Affiliation:

1. Department of Dermatology, Ruhr-University Bochum , Bochum , Germany

2. Department of Dermatology, Christian Hospital Unna , Unna , Germany

3. Department of Dermatology, Dortmund Hospital gGmbH and Faculty of Health, University of Witten-Herdecke , Dortmund , Germany

4. Translational Skin Cancer Research, DKTK Partner Site Essen/Düsseldorf, West German Cancer Center, Dermatology, University Duisburg-Essen , Essen , Germany

5. German Cancer Research Center (DKFZ) , Heidelberg , Germany

Abstract

Hydroxymethylation plays a significant role in cancer development and progression. We hypothesized that hydroxymethylation markers may have prognostic potential in AFX/PDS (atypical fibroxanthoma/pleomorphic dermal sarcoma) as also observed in other tumours. Moreover, we wanted to find out whether hydroxymethylation markers might aid differentiation between AFX and PDS.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/bjd/advance-article-pdf/doi/10.1093/bjd/ljae171/57955561/ljae171.pdf

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