Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice
Author:
Affiliation:
1. Department of Biology,
2. Department of Biochemistry and Biomedical Sciences and
3. Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
Publisher
Oxford University Press (OUP)
Subject
Genetics(clinical),Genetics,Molecular Biology,General Medicine
Link
http://academic.oup.com/hmg/article-pdf/22/19/3960/25860770/ddt250.pdf
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4. Ganglioside GM2 N-acetyl-beta-D-galactosaminidase activity in cultured fibroblasts of late-infantile and adult GM2 gangliosidosis patients and of healthy probands with low hexosaminidase level;Conzelmann;Am. J. Hum. Genet.,1983
5. Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism;Sango;Nat. Genet.,1995
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