Affiliation:
1. School of Biotechnology and Health Sciences, Wuyi University , Jiangmen 529020 , P.R. China
2. International Healthcare Innovation Institute (Jiangmen) , Jiangmen 529020 , P.R. China
3. Department of Chemistry, University of Liverpool , Liverpool L69 7ZD , UK
4. Vector Biology, Liverpool School of Tropical Medicine , Liverpool L3 5QA , UK
Abstract
Abstract
Aedes albopictus (Skuse) is a vector of several arboviruses, such as dengue, chikungunya, West Nile, and Zika viruses. At present, the use of synthetic insecticides is the main vector control strategy. However, the widespread and long-term use of insecticides has aroused several problems, including insecticide resistance, environmental pollution, and non-target species effects, thereby encouraging researchers to search for new alternatives derived from natural products. In recent decades, essential oils (EOs) as natural alternatives to control mosquitoes have received increasing attention. In the initial larvicidal activity screen, two Rutaceae plants (Citrus aurantium and Citrus paradisi) EOs were selected and evaluated for killing Ae. albopictus larvae. The LC50 values of C. aurantium and C. paradisi EOs against Ae. albopictus were 91.7 and 100.9 ppm, respectively. The main components of C. aurantium EO include diethyl o-phthalate (37.32%), limonene (10.04%), and methyl dihydrojasmonate (6.48%). The main components of C. paradisi EO include limonene (60.51%), diethyl o-phthalate (11.75%), linalool (7.90%), and styralyl acetate (6.28%). Among these main components of the two EOs, limonene showed potent larvicidal activity, with the LC50 value of 39.7 ppm. The nanoemulsions of limonene were prepared and characterized. The duration of larvicidal activity was greater in the limonene nanoemulsions than when limonene was applied in solvent. This study demonstrates that EOs of plants in family Rutaceae are a potential resource to develop new larvicides, and nanoemulsification is an effective method for improving the physicochemical properties and efficacy of natural products as larvicides.
Funder
High-level Talents of Wuyi University
Project of Science and Technology Innovation Strategy in Guangdong Province
Jiangmen Science and Technology Project of Basic and Theoretical Science Research
Project of Doctoral Research Initiation in Wuyi University
Project of Innovative and Entrepreneurship for College Students in Wuyi University
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Insect Science,General Veterinary,Parasitology
Cited by
5 articles.
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