In VitroAnti-CandidaActivity ofZataria multifloraBoiss

Abstract

Zataria multifloraBoiss known as Avishan Shirazi (in Iran) is one of the valuable Iranian medicinal plants. The aim of study was to evaluate anti-Candidaactivity ofZ. multifloraagainst different species ofCandida in vitro. Anti-Candidaactivity of the aqueous, ethanolic and methanolic maceration extract of the aerial parts ofZ. multiflora Boisswas studiedin vitro. Anti-Candidaactivity againstCandidaspecies was done using serial dilutions of extracts in Sabouraud's dextrose agar. Minimal inhibitory concentration (MIC) of the methanolic and ethanolic extracts was 70.7 and 127 mg l−1, respectively. Aqueous extract showed no remarkable activity againstCandidaspecies. We conclude that methanolic extract of the aerial parts ofZ. multifloraBoiss has more anti-Candidaeffect at 70.7 mg l−1compared to ethanolic extract 127 mg l−1. In addition, the isolates ofCandida parapsilosiswere more susceptible to methanolic extract than other tested species.