An effective diagnostic index for lymphoma-associated hemophagocytic syndrome
Author:
Affiliation:
1. From the Senior Department of Haematology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
Funder
Department of Health of Zhejiang Province
Publisher
Oxford University Press (OUP)
Subject
General Medicine
Link
http://academic.oup.com/qjmed/article-pdf/111/8/541/25415570/hcy103.pdf
Reference30 articles.
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2. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3);Feldmann;Cell,2003
3. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11;Zur;Hum Mol Genet,2005
4. Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11;Zur;Am J Hum Genet,2009
5. Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells;Cote;J Clin Invest,2009
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