Fracture prevention: a population-based intervention delivered in primary care

Author:

Hoggard K1,Hart S2,Birchall J1,Kirk S3,Goff I4,Grove M4,Newton J25

Affiliation:

1. Interface Clinical Services Ltd, Schofield House, Gate Way Drive, Yeadon Leeds LS19 7XY, UK

2. Academic Health Science Network–North East and North Cumbria, Room 2.13, Biomedical Research Building, The Campus for Ageing and Vitality, Nuns’ Moor Road, Newcastle upon Tyne NE4 5PL, UK

3. NHS Newcastle Gateshead CCG, Newcastle upon Tyne, UK

4. Department of Rheumatology, Northumbria Healthcare NHS Foundation Trust

5. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK

Abstract

Abstract Background Osteoporosis is common, increasing as the population ages and has significant consequences including fracture. Effective treatments are available. Aim To support proactive fracture risk assessment (FRAX) and optimizing treatment for high-risk patients in primary care. Design Clinical cohort Setting November 2017 to November 2018, support was provided to 71 practices comprising 69 of 90 practices within two National Health Service Clinical Commissioning Groups areas. Total population 579 508 (207 263 aged over 50 years). Participants FRAX (National Institute for Care and Clinical Excellence, NICE CG146) in (i) males aged 75 years and over, (ii) females aged 65 years and over, (iii) females aged under 65 years and males aged under 75 years with risk factors and (iv) under 50 years with major risk factors. Results A total of 158 946 met NICE CG146, 11 961 were coded with an osteoporosis diagnosis (7.5%), of those, 42% were prescribed treatment with a bone sparing agent (BSA). In total, 6942 were assessed to initiate BSA. Thirty percent of untreated osteoporosis diagnosis patients had never been prescribed BSA. Even when prescribed, 1700 people (35%) were for less than minimum recommended duration. Of the total 9784 patients within the FRAX recommended to treat threshold, 3197 (33%) were currently treated with BSA and 3684 (37%) had no history of ever receiving BSA. From untreated patients, expected incidence of 875 fractures over a 3-year period (approximately £3.4 million). Treatment would prevent 274 fractures (cost reduction: £1 274 045, with prescribing costs: saving £805 145 after 3 years of treatment). Conclusion Underdiagnosis and suboptimal treatment of osteoporosis was identified. Results suggest that implementing NICE guidance and optimizing treatment options in practice is possible and could prevent significant fractures.

Funder

Amgen

Academic Health Science Network

North East and North Cumbria

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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