Correlation of Intravenous Vitamin C Injection and Plasma Albumin Level in Burnt Rats (Experimental Animal Study)

Abstract

Abstract Background Burn is tissue injury caused by heat, radiation, electricity, contact with hot objects or chemicals. It’s a global public health problem accounting for an estimated 180000 death annually according to WHO. Aim of the Work To detect the efficacy of intravenous vitamin C and plasma albumin level in burnt rats. Materials and Methods This study was an experimental study on 14 rats only not including any human and they were divided into two groups: Group A that represented burnt rats that won’t be injected with parenteral vitamin C and Group B represented burnt rats that will be injected with parenteral vitamin C. Results There was no statistically significant difference found between two groups regarding albumin level and total proteins level before burn and Post burn 8h. There was highly statistically significant difference between Albumin level and total proteins level before Burn, Post Burn 8h level and Post Burn 24h level. Conclusion It is concluded that vitamin C holds potential as a powerful adjunct in burn resuscitation and it may be safe and decreases fluid requirement in the acute phase after burn injury.