GlobeCorr: interactive globe-based visualization for correlation datasets

Author:

Arab Mariam1,Woods Nolan1,Garlock Emma S1ORCID,Winsor Geoffrey L1ORCID,Parks Jaclyn P23,Jia Baofeng1ORCID,Doiron Dany4,Takaro Tim K2,Brook Jeffrey R5,Brinkman Fiona S L1

Affiliation:

1. Molecular Biology and Biochemistry, Simon Fraser University , Burnaby, BC V5A 1S6, Canada

2. Faculty of Health Sciences, Simon Fraser University , Burnaby, BC V5A 1S6, Canada

3. Cancer Control Research, BC Cancer Research Institute , Vancouver, BC V5Z 1L3, Canada

4. Research Institute of McGill University Health Centre , Montreal, QC H4A 3J1, Canada

5. Dalla Lana School of Public Health, University of Toronto , Toronto, ON M5T 3M7, Canada

Abstract

Abstract Motivation Increasingly complex omics datasets are being generated, along with associated diverse categories of metadata (environmental, clinical, etc.). Looking at the correlation between these variables can be critical to identify potential confounding factors and novel relationships. To date, some correlation globe software has been developed to aid investigations; however, they lack secure, dynamic visualization capability. Results GlobeCorr.ca is a web-based application designed to provide user-friendly, interactive visualization and analysis of correlation datasets. Users load tabular data listing pairwise variables and their correlation values, and GlobeCorr creates a dynamic visualization using ribbons to represent positive and negative correlations, optionally grouped by domain/category (such as microbiome taxa against other metadata). GlobeCorr runs securely (locally on a user’s computer) and provides a simple method for users to visualize and summarize complex datasets. This tool is applicable to a wide range of disciplines and domains of interest, including the bioinformatics/microbiome and metadata examples provided within. Availability and Implementation See https://GlobeCorr.ca; Code provided under an open source MIT license: https://github.com/brinkmanlab/globecorr.

Funder

Genome Canada and the CIHR IMPACTT Project

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Embryology,Anatomy

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