1. Research Institute for Microbial Diseases, Department of Genome Informatics, Osaka University , Suita 565-0871, Japan
2. Department of Applied Mathematics and Statistics, Stony Brook University , Stony Brook, NY 11794-5252, USA
3. Laufer Center for Physical and Quantitative Biology, Stony Brook University , Stony Brook, NY 11794-5252, USA
4. Faculty of Data Science, Shiga University , Hikone 522-8522, Japan
5. Immunology Frontier Research Center, Department of Systems Immunology, Osaka University , Suita 565-0871, Japan