The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection

Author:

Hausenloy Derek J12345,Chilian William6,Crea Filippo7,Davidson Sean M4,Ferdinandy Peter89,Garcia-Dorado David1011,van Royen Niels12,Schulz Rainer13,Heusch Gerd14

Affiliation:

1. Cardiovascular & Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore

2. National Heart Research Institute Singapore, National Heart Centre, Singapore, Singapore

3. Yong Loo Lin School of Medicine, National University Singapore, Singapore, Singapore

4. The Hatter Cardiovascular Institute, University College London, London, UK

5. The National Institute of Health Research, University College London Hospitals Biomedical Research Centre, Research & Development, London, UK

6. Department of Integrative Medical Sciences, Northeast Ohio Medical University, 4209 State Route 44, Rootstown, USA

7. Department of Cardiovascular and Thoracic Sciences, F. Policlinico Gemelli—IRCCS, Università Cattolica Sacro Cuore, Roma, Italy

8. Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary

9. Pharmahungary Group, Szeged, Hungary

10. Department of Cardiology, Vascular Biology and Metabolism Area, Vall d’Hebron University Hospital and Research Institute (VHIR), Universitat Autónoma de Barcelona, Barcelona, Spain

11. Instituto CIBER de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain

12. Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands

13. Institute of Physiology, Justus-Liebig University Giessen, Giessen, Germany

14. Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany

Funder

National Institute for Health Research University College London Hospitals Biomedical Research Centre

British Heart Foundation

Duke-National University Singapore Medical School

Singapore Ministry of Health’s National Medical Research Council

Clinician Scientist-Senior Investigator

Collaborative Centre

Singapore Ministry of Education Academic Research Fund Tier 2

German Research Foundation

National Research, Development and Innovation Office of Hungary

OTKA

Higher Education Institutional Excellence Programme of the Ministry of Human Capacities in Hungary

Therapeutic Development

Semmelweis University

Instituto de Salud Carlos III

CIBERCV-Instituto de Salud Carlos III

European Regional Development Fund-FEDER

COST Action EU-CARDIOPROTECTION

European Cooperation in Science and Technology

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Reference200 articles.

1. Myocardial reperfusion injury;Yellon;N Engl J Med,2007

2. Evolving therapies for myocardial ischemia/reperfusion injury;Ibanez;J Am Coll Cardiol,2015

3. Reflection of cardioprotection by remote ischemic perconditioning in attenuated ST-segment elevation during ongoing coronary occlusion in pigs: evidence for cardioprotection from ischemic injury;Kleinbongard;Circ Res,2018

4. Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations;Hausenloy;Eur Heart J,2017

5. The pathophysiology of acute myocardial infarction and strategies of protection beyond reperfusion: a continual challenge;Heusch;Eur Heart J,2017

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