Endoplasmic reticulum stress-related cancer-associated fibroblast confers adverse prognosis and therapeutic vulnerability in skull base chordoma

Author:

Li Mingxuan12,Xiong Yujia13,Bai Jiwei12,Zhang Yazhuo12ORCID

Affiliation:

1. Beijing Neurosurgical Institute, Capital Medical University , Beijing , China

2. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University , Beijing , China

3. Department of Pathology, West China Hospital, Sichuan University , Chengdu , China

Funder

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Reference6 articles.

1. Integrating single-cell and spatial transcriptomics reveals endoplasmic reticulum stress-related CAF subpopulations associated with chordoma progression;Zhang;Neuro Oncol,2023

2. Gene expression profiling identifies two chordoma subtypes associated with distinct molecular mechanisms and clinical outcomes;Bai;Clin Cancer Res.,2023

3. Inferring tumour purity and stromal and immune cell admixture from expression data;Yoshihara;Nat Commun.,2013

4. xCell: digitally portraying the tissue cellular heterogeneity landscape;Aran;Genome Biol.,2017

5. Targeted therapy for chordoma: key molecular signaling pathways and the role of multimodal therapy;Akinduro;Target Oncol,2021

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