EPID-21. EPIDEMIOLOGY OF MALIGNANT GLIOMAS IN KOREA USING NATIONWIDE BIG DATA FROM 2007 TO 2017

Abstract

Abstract The purpose of the study of the study is to investigate the incidence, prevalence, and survival of malignant glioma (MG) using population-based Korean National Health Insurance Database (NHID) data. We identified patients with MG as C71 codes in KCD 5–7 according to ICD-10 from 2007 to 2017. Epidemiological characteristics of MG, including annual incidence, prevalence, mortality rates, and survival rates, were collected and analyzed according to socioeconomic state (SES) and treatment modalities. 45,066 new patients with MG were identified from 2007 to 2017. An age-adjusted incidence of 7.47 per 100,000 people. The mean age at diagnosis was 54 years. The male to female ratio was 1.11. Mortality and survival probability were analyzed among total subjects and in subgroups. The mortality of female patients was lower than that of male patients (hazard ration, 0.69; 95% CI, 0.67–0.71), and younger age and higher income had significantly lower mortality rate. The 1-, 3-, 5-, and 10-year total relative survival rates were estimated at 63.4%, 46.2%, 39.4%, and 34.8%, respectively. This is the first population-based study to determine the incidence and prevalence of MG according to epidemiological characteristics in Korea using NHID data. Our study found that female sex and high SES were factors that significantly lowered the mortality rate in MG, and younger groups and operated patients showed significantly higher survival rates.