Phase II trial of dacomitinib, a pan–human EGFR tyrosine kinase inhibitor, in recurrent glioblastoma patients with EGFR amplification

Author:

Sepúlveda-Sánchez Juan Manuel,Vaz María Ángeles,Balañá Carmen,Gil-Gil Miguel,Reynés Gaspar,Gallego Óscar,Martínez-García María,Vicente Elena,Quindós María,Luque Raquel,Ramos Ana,Ruano Yolanda,Pérez-Segura Pedro,Benavides Manuel,Sánchez-Gómez Pilar,Hernández-Laín Aurelio

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Neurology (clinical),Oncology

Reference34 articles.

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3. EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis;Acta Neuropathol,2013

4. Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion;Cancer Res,2002

5. Efficacy of erlotinib in patients with relapsed gliobastoma multiforme who expressed EGFRVIII and PTEN determined by immunohistochemistry;J Neurooncol,2014

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