Targeted copy number analysis outperforms histologic grading in predicting patient survival for WHO grades II/III IDH-mutant astrocytomas
Author:
Affiliation:
1. Department of Pathology, Division of Neuropathology, University of Washington School of Medicine, Seattle, Washington
2. Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington
Funder
Alzheimer’s Disease Research Center
Publisher
Oxford University Press (OUP)
Subject
Cancer Research,Clinical Neurology,Oncology
Link
http://academic.oup.com/neuro-oncology/advance-article-pdf/doi/10.1093/neuonc/noz052/28498550/noz052.pdf
Reference6 articles.
1. Grading of diffuse astrocytic gliomas: a review of studies before and after the advent of IDH testing;von Deimling;Semin Neurol.,2018
2. IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas;Olar;Acta Neuropathol.,2015
3. Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery;Cimino;Acta Neuropathol Commun,2017
4. Novel, improved grading system(s) for IDH-mutant astrocytic gliomas;Shirahata;Acta Neuropathol.,2018
5. DNA methylation-based classification of central nervous system tumours;Capper;Nature.,2018
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1. The biological significance of tumor grade, age, enhancement, and extent of resection in IDH-mutant gliomas: How should they inform treatment decisions in the era of IDH inhibitors?;Neuro-Oncology;2024-06-24
2. A novel grading system combining histological grade and CDKN2A homozygous and hemizygous deletion to predict prognosis in IDH-mutant astrocytoma;Journal of Neuropathology & Experimental Neurology;2024-01-04
3. Genetic alterations that deregulate RB and PDGFRA signaling pathways drive tumor progression in IDH2-mutant astrocytoma;Acta Neuropathologica Communications;2023-11-27
4. Novel insight into histological and molecular astrocytoma, IDH‐mutant, Grade 4 by the updated WHO classification of central nervous system tumors;Cancer Medicine;2023-09
5. A novel MRI-based deep learning networks combined with attention mechanism for predicting CDKN2A/B homozygous deletion status in IDH-mutant astrocytoma;European Radiology;2023-08-08
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