Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages

Author:

Baskaran Sathishkumar1,Mayrhofer Markus2,Kultima Hanna Göransson2,Bergström Tobias1,Elfineh Lioudmila1,Cavelier Lucia1,Isaksson Anders2,Nelander Sven1

Affiliation:

1. Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Sweden

2. Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Sweden

Funder

Swedish Research Council

Swedish Cancer Society

Swedish Foundation fro Strategic Research

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Clinical Neurology,Oncology

Reference35 articles.

1. Radiotherapy plus concomitant\and adjuvant temozolomide for glioblastoma;Stupp;N Engl J Med,2005

2. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens;Pollard;Cell Stem Cell,2009

3. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines;Lee;Cancer Cell,2006

4. The human glioblastoma cell culture resource: validated cell models representing all molecular subtypes;Xie;EBioMedicine,2015

5. Case-specific potentiation of glioblastoma drugs by pterostilbene;Schmidt;Oncotarget,2016

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