Reply to “Targeting cholesterol homeostasis through inhibiting: An Achilles’ heel for glioblastoma?”-Reference-Cited by-同舟云学术

Reply to “Targeting cholesterol homeostasis through inhibiting: An Achilles’ heel for glioblastoma?”

Published:2023-08-25 Issue:11 Volume:25 Page:2103-2104
ISSN:1522-8517
Container-title:Neuro-Oncology
language:en
Short-container-title:

Author:

Gu Danling¹²,You Hao¹²,Gao Jiancheng¹²³,You Yongping²³,Rich Jeremy N⁴⁵,Zhang Junxia²³,Wang Xiuxing¹²⁶

Affiliation:

1. National Health Commission Key Laboratory of Antibody Techniques, Department of Cell Biology, Jiangsu Provincial Key Laboratory of Human Functional Genomics, School of Basic Medical Sciences, Nanjing Medical University , Jiangsu , China

2. Institute for Brain Tumors, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University , Jiangsu , China

3. Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University , Jiangsu , China

4. University of Pittsburgh Medical Center Hillman Cancer Center , Pittsburgh, PA , USA

5. Department of Neurology, University of Pittsburgh School of Medicine , Pittsburgh, PA , USA

6. Jiangsu Cancer Hospital, Affiliated Cancer Hospital of Nanjing Medical University , Jiangsu , China

Funder

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Neurology (clinical),Oncology

Link

https://academic.oup.com/neuro-oncology/advance-article-pdf/doi/10.1093/neuonc/noad146/51250778/noad146.pdf

Reference8 articles.

1. SREBP2 maintains glioblastoma stem cells through keeping the balance between cholesterol biosynthesis and uptake;Gu;Neuro Oncol,2023

2. Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques;Tang;Cell Metab.,2011

3. Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig;Radhakrishnan;Proc Natl Acad Sci U S A.,2007

4. Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis;Geng;Clin Cancer Res.,2016

5. Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity;Yan;Cancer Cell,2023