Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma

Author:

Gan Hui K123,Reardon David A4,Lassman Andrew B5,Merrell Ryan6,van den Bent Martin7,Butowski Nicholas8,Lwin Zarnie9,Wheeler Helen10,Fichtel Lisa11,Scott Andrew M123,Gomez Erica J12,Fischer JuDee12,Mandich Helen12,Xiong Hao12,Lee Ho-Jin12,Munasinghe Wijith P12,Roberts-Rapp Lisa A12,Ansell Peter J12,Holen Kyle D12,Kumthekar Priya13

Affiliation:

1. Department of Medical Oncology, Austin Health and Olivia Newton-John Cancer Research Institute, Melbourne, Victoria, Australia

2. School of Cancer Medicine, La Trobe University School of Cancer Medicine, Melbourne, Victoria, Australia

3. Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia

4. Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

5. Department of Neurology & Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, USA

6. Department of Neurology, NorthShore University HealthSystem, Evanston, Illinois, USA

7. Neuro-Oncology Unit, Erasmus MC Cancer Center, Rotterdam, the Netherlands

8. Department of Neurological Surgery, University of California, San Francisco, California, USA

9. Department of Medical Oncology, University of Queensland School of Medicine, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia

10. Medical Oncology, Royal North Shore Hospital, Sydney, New South Wales, Australia

11. South Texas Accelerated Research Therapeutics, San Antonio, Texas, USA

12. AbbVie Inc., North Chicago, Illinois, USA

13. Department of Neurology, Northwestern University, Chicago, Illinois, USA

Funder

AbbVie

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Neurology (clinical),Oncology

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