Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T

Author:

Paech Daniel1ORCID,Windschuh Johannes23,Oberhollenzer Johanna1,Dreher Constantin1,Sahm Felix45,Meissner Jan-Eric2,Goerke Steffen2,Schuenke Patrick2,Zaiss Moritz6,Regnery Sebastian7,Bickelhaupt Sebastian1,Bäumer Philipp12,Bendszus Martin8,Wick Wolfgang9,Unterberg Andreas10,Bachert Peter,Ladd Mark Edward211,Schlemmer Heinz-Peter1,Radbruch Alexander112

Affiliation:

1. German Cancer Research Center, Division of Radiology, Heidelberg, Germany

2. German Cancer Research Center, Division of Medical Physics in Radiology, Heidelberg, Germany

3. Department of Radiology, New York University Langone Medical Center, New York, New York, USA

4. Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany

5. CCU Neuropathology, German Consortium for Translational Cancer Research, German Cancer Research Center, Heidelberg, Germany

6. Max-Planck-Institute for Biological Cybernetics, Magnetic Resonance Center, Tuebingen, Germany

7. Department of Radiooncology, University Hospital Heidelberg, Heidelberg, Germany

8. Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany

9. Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany

10. Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany

11. Faculty of Physics and Astronomy and Faculty of Medicine, University of Heidelberg, Heidelberg, Germany

12. Department of Radiology, University Hospital Essen, Essen, Germany

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Clinical Neurology,Oncology

Reference50 articles.

1. Prevalence estimates for primary brain tumors in the United States by age, gender, behavior, and histology;Porter;Neuro Oncol,2010

2. Malignant glioma: ESMO clinical recommendations for diagnosis, treatment and follow-up;Stupp;Ann Oncol,2009

3. Malignant gliomas in adults;Wen;N Engl J Med,2008

4. MGMT gene silencing and benefit from temozolomide in glioblastoma;Hegi;N Engl J Med,2005

5. Concepts in glioma immunotherapy;Platten;Cancer Immunol Immunother,2016

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