Mucosal Profiles of Immune Molecules Related to T Helper and Regulatory T Cells Predict Future Relapse in Patients With Quiescent Ulcerative Colitis

Author:

Fukaura Keita1,Iboshi Yoichiro2,Ogino Haruei1,Ihara Eikichi1ORCID,Nakamura Kazuhiko3,Nishihara Yuichiro1,Nishioka Kei1,Chinen Takatoshi1,Iwasa Tsutomu1,Aso Akira1,Goto Ayako1,Haraguchi Kazuhiro3,Akiho Hirotada4,Harada Naohiko2,Ogawa Yoshihiro1

Affiliation:

1. Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

2. Department of Gastroenterology, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan

3. Department of Gastroenterology, Harasanshin Hospital, Fukuoka, Japan

4. Department of Gastroenterology, Kitakyushu Municipal Medical Center, Fukuoka, Japan

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Reference51 articles.

1. Diagnostics of inflammatory bowel disease;Nikolaus;Gastroenterology.,2007

2. Unravelling the pathogenesis of inflammatory bowel disease;Xavier;Nature.,2007

3. Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases;Strober;Gastroenterology.,2011

4. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5;Fuss;J Immunol.,1996

5. Nonclassical CD1D-restricted NK T cells that produce IL-13 characterize an atypical th2 response in ulcerative colitis;Fuss;J Clin Invest.,2004

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