Pharmacokinetics of rifampicin in adult TB patients and healthy volunteers: a systematic review and meta-analysis

Author:

Stott K E1ORCID,Pertinez H1,Sturkenboom M G G2,Boeree M J3,Aarnoutse R3,Ramachandran G4,Requena-Méndez A5,Peloquin C6,Koegelenberg C F N7,Alffenaar J W C2,Ruslami R8,Tostmann A9,Swaminathan S10,McIlleron H11,Davies G112

Affiliation:

1. Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

2. Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

3. Radboud University Medical Center, Nijmegen, The Netherlands

4. Department of Biochemistry and Clinical Pharmacology, National Institute for Research in Tuberculosis, Chennai, India

5. CRESIB, Barcelona Institute for Global Health, University of Barcelona, Barcelona, Spain

6. College of Pharmacy and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA

7. Department of Pulmonology, Stellenbosch University & Tygerberg Academic Hospital, Cape Town, South Africa

8. Department of Pharmacology and Therapy, Universitas Padjadjaran, Bandung, Indonesia

9. Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands

10. Indian Council of Medical Research, New Delhi, India

11. Division of Clinical Pharmacology, University of Cape Town, Cape Town, South Africa

12. Institute of Global Health, University of Liverpool, Liverpool, UK

Funder

Wellcome Trust

South African National Research Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference51 articles.

1. Advances in the development of new tuberculosis drugs and treatment regimens;Zumla;Nat Rev Drug Discov,2013

2. Why do we use 600 mg of rifampicin in tuberculosis treatment?;van Ingen;Clin Infect Dis,2011

3. Therapeutic drug monitoring: principles and applications in mycobacterial infections;Peloquin;Drug Therapy,1992

4. Low antituberculosis drug concentrations in patients with AIDS;Peloquin;Ann Pharmacother,1996

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