Analysis of a Large Severe Acute Respiratory Syndrome Coronavirus 2 (Alpha) Outbreak in a Catalan Prison Using Conventional and Genomic Epidemiology

Author:

Bordoy Antoni E12,Vallès Xavier1,Fernández-Náger Juan3,Sánchez-Roig Montserrat3,Fernández-Recio Juan4,Saludes Verónica125,Noguera-Julian Marc67ORCID,Blanco Ignacio28,Martró Elisa125ORCID, ,Balcázar E P,Díaz M R,Encarnación R,Fuentes M,Gallego C,Pale A M,Puig P,Moreno E A,Puertolas A,Chouldry G,Sala I,Jiménez A G,Armenteros B,Alvo J,Gómez S,Guillament M,Martínez D,Martin A,Moruno M A,Parra N,Puig A,Rodríguez F J,Sánchez M,Varoucha A C,Moreno M,Martínez J,Huguet S,Sánchez A,Alonso T,Garcia M,Prat E,Aranda A,Arguelles M J,Azqueta J,Cruz E,Egido R M,Galvany R,Garcia B,González M,González V,Infante J A,Latorre C,Márquez P,Muñoz I,Porras M,Ramos M,Escamilla M,Santalucía J,Riquelme M,Rastrollo L,Pedrerol M,Caraballo V,Fontan J,Verú M,Conill V,Soler L,Panisello Yagüe D,Casañ C,Clarà G,Giménez M,Guerrero-Murillo M,Cardona P J,Marco Andrés

Affiliation:

1. Germans Trias i Pujol Research Institute (IGTP) , Badalona

2. Microbiology Department, Northern Metropolitan Clinical Laboratory, Hospital Universitari Germans Trias i Pujol , Badalona

3. Primary Penitentiary Care Team, La Roca del Vallès 1 , Barcelona

4. Instituto de Ciencias de la Vid y del Vino, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad de La Rioja, Gobierno de La Rioja , Logroño

5. Epidemiology and Public Health, Networking Biomedical Research Centre (CIBERESP) , Madrid

6. Institut de Recerca de la SIDA-IrsiCaixa, Germans Trias i Pujol Research Institute , Badalona

7. AIDS and Infectious Diseases Department, University of Vic–Central University of Catalonia (UVic-UCC) , Vic

8. Clinical Genetics Department, Northern Metropolitan Clinical Laboratory, Hospital Universitari Germans Trias i Pujol , Badalona

Abstract

Abstract Enforcing strict protocols that prevent transmission of airborne infections in prisons is challenging. We examine a large severe acute respiratory syndrome coronavirus 2 outbreak in a Catalan penitentiary center in February–April 2021, prior to vaccination deployment. The aim was to describe the evolution of the outbreak using classical and genomic epidemiology and the containment strategy applied. The outbreak was initially detected in 1 module but spread to 4, infecting 7 staff members and 140 incarcerated individuals, 6 of whom were hospitalized (4.4%). Genomic analysis confirmed a single origin (B.1.1.7). Contact tracing identified transmission vectors between modules and prevented further viral spread. In future similar scenarios, the control strategy described here may help limit transmission of airborne infections in correctional settings.

Publisher

Oxford University Press (OUP)

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