Antibody Duration After Infection From SARS-CoV-2 in the Texas Coronavirus Antibody Response Survey-Reference-Cited by-同舟云学术

Antibody Duration After Infection From SARS-CoV-2 in the Texas Coronavirus Antibody Response Survey

Published:2022-05-06 Issue:2 Volume:227 Page:193-201
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Swartz Michael D¹^ORCID,DeSantis Stacia M¹,Yaseen Ashraf¹,Brito Frances A¹,Valerio-Shewmaker Melissa A²,Messiah Sarah E³,Leon-Novelo Luis G¹,Kohl Harold W⁴⁵,Pinzon-Gomez Cesar L¹,Hao Tianyao¹,Zhang Shiming¹,Talebi Yashar¹,Yoo Joy¹,Ross Jessica R¹,Gonzalez Michael O¹,Wu Leqing¹,Kelder Steven H⁴,Silberman Mark⁶,Tuzo Samantha⁶,Pont Stephen J⁷,Shuford Jennifer A⁷,Lakey David⁸,Boerwinkle Eric¹

Affiliation:

1. The University of Texas Health Science Center in Houston, School of Public Health in Houston , Houston, Texas , USA

2. The University of Texas Health Science Center in Houston, School of Public Health in Brownsville , Brownsville, Texas , USA

3. The University of Texas Health Science Center in Houston, School of Public Health in Dallas , Dallas, Texas , USA

4. The University of Texas Health Science Center in Houston, School of Public Health in Austin , Austin, Texas , USA

5. The University of Texas at Austin, College of Education, Department of Kinesiology and Health Education , Austin, Texas , USA

6. Clinical Pathology Laboratories , Austin, Texas , USA

7. Texas Department of State Health Services , Austin, Texas , USA

8. University of Texas System, Office of Health Affairs , Austin, Texas , USA

Abstract

Abstract Understanding the duration of antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that causes COVID-19 is important to controlling the current pandemic. Participants from the Texas Coronavirus Antibody Response Survey (Texas CARES) with at least 1 nucleocapsid protein antibody test were selected for a longitudinal analysis of antibody duration. A linear mixed model was fit to data from participants (n = 4553) with 1 to 3 antibody tests over 11 months (1 October 2020 to 16 September 2021), and models fit showed that expected antibody response after COVID-19 infection robustly increases for 100 days postinfection, and predicts individuals may remain antibody positive from natural infection beyond 500 days depending on age, body mass index, smoking or vaping use, and disease severity (hospitalized or not; symptomatic or not).

Funder

Texas Department of State Health Services

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiac167/43575509/jiac167.pdf

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