A Trimeric, V2-Deleted HIV-1 Envelope Glycoprotein Vaccine Elicits Potent Neutralizing Antibodies but Limited Breadth of Neutralization in Human Volunteers-Reference-Cited by-同舟云学术

A Trimeric, V2-Deleted HIV-1 Envelope Glycoprotein Vaccine Elicits Potent Neutralizing Antibodies but Limited Breadth of Neutralization in Human Volunteers

Published:2011-04-15 Issue:8 Volume:203 Page:1165-1173
ISSN:1537-6613
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Spearman Paul¹,Lally Michelle A.²,Elizaga Marnie³,Montefiori David⁴,Tomaras Georgia D.⁴,McElrath M. Juliana³,Hural John³,De Rosa Stephen C.³,Sato Alicia³,Huang Yunda³,Frey Sharon E.⁵,Sato Paul⁶,Donnelly John⁷,Barnett Susan⁷,Corey Lawrence J.³,

Affiliation:

1. Department of Pediatrics, Emory University and Children's Healthcare of Atlanta, Georgia

2. Department of Medicine, Miriam Hospital and Alpert Medical School of Brown University, Providence, Rhode Island

3. Fred Hutchinson Cancer Research Center, Seattle, Washington

4. Department of Surgery, Duke University School of Medicine, Durham, North Carolina

5. Department of Internal Medicine, St. Louis University School of Medicine, Missouri

6. Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland

7. Novartis Vaccines and Diagnostics, Cambridge, Massachusetts

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

http://academic.oup.com/jid/article-pdf/203/8/1165/16865585/jiq175.pdf

Reference36 articles.

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2. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand;Pitisuttithum;J Infect Dis,2006

3. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial;Buchbinder;Lancet,2008

4. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand;Rerks-Ngarm;N Engl J Med,2009

5. Purification, characterization, and immunogenicity of a soluble trimeric envelope protein containing a partial deletion of the V2 loop derived from SF162, an R5-tropic human immunodeficiency virus type 1 isolate;Srivastava;J Virol,2003

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