Higher T-Cell Responses Induced by DNA/rAd5 HIV-1 Preventive Vaccine Are Associated With Lower HIV-1 Infection Risk in an Efficacy Trial

Author:

Janes Holly E.1,Cohen Kristen W.1,Frahm Nicole1,De Rosa Stephen C.1,Sanchez Brittany1,Hural John1,Magaret Craig A.1,Karuna Shelly1,Bentley Carter1,Gottardo Raphael1,Finak Greg1,Grove Douglas2,Shen Mingchao1,Graham Barney S.3,Koup Richard A.3,Mulligan Mark J.4,Koblin Beryl5,Buchbinder Susan P.6,Keefer Michael C.7,Adams Elizabeth8,Anude Chuka9,Corey Lawrence1,Sobieszczyk Magdalena10,Hammer Scott M.10,Gilbert Peter B.1,McElrath M. Juliana1

Affiliation:

1. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, and

2. The Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, Washington;

3. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland;

4. Emory Vaccine Center, Emory University, Atlanta, Georgia;

5. Laboratory of Infectious Disease Prevention, New York Blood Center, New York;

6. Departments of Medicine and Epidemiology/Biostatistics, University of California San Francisco;

7. University of Rochester Medical Center, School of Medicine and Dentistry, New York;

8. Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, and

9. Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland; and

10. Division of Infectious Diseases, Columbia University College of Physicians and Surgeons, New York

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

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