Safety and Immunogenicity of an Adjuvanted Herpes Zoster Subunit Candidate Vaccine in HIV-Infected Adults: A Phase 1/2a Randomized, Placebo-Controlled Study

Author:

Berkowitz Elchonon M.1,Moyle Graeme2,Stellbrink Hans-Jürgen3,Schürmann Dirk4,Kegg Stephen5,Stoll Matthias6,El Idrissi Mohamed7,Oostvogels Lidia7,Heineman Thomas C.1,Brockmeyer Norbert,deJesus Edwin,Esser Stefan,Hawkins Trevor,Lalezari Jacob,Orkin Chloe,Schneider Stefan,

Affiliation:

1. GlaxoSmithKline Vaccines, King of Prussia, Pennsylvania

2. Chelsea and Westminster Hospital

3. Infektionsmedizinisches Centrum Hamburg

4. Department of Infectious Diseases and Pulmonary Medicine, Charité–Universitätsmedizin Berlin

5. Queen Elizabeth Hospital NHS Trust, The Trafalgar Clinic, London, United Kingdom

6. Medizinische Hochschule Hannover, Zentrum Innere Medizin, Klinische Immunologie II, Germany

7. GlaxoSmithKline Vaccines, Wavre, Belgium

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference30 articles.

1. Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP);Harpaz;MMWR Recomm Rep,2008

2. Herpes zoster among persons living with HIV in the current antiretroviral therapy era;Blank;J Acquir Immune Defic Syndr,2012

3. Herpes zoster and human immunodeficiency virus infection;Buchbinder;J Infect Dis,1992

4. A population-based study of the incidence and complication rates of herpes zoster before zoster vaccine introduction;Yawn;Mayo Clin Proc,2007

5. Immune responses to varicella-zoster virus;Arvin;Infect Dis Clin North Am,1996

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