A Lipid/DNA Adjuvant–Inactivated Influenza Virus Vaccine Protects Rhesus Macaques From Uncontrolled Virus Replication After Heterosubtypic Influenza A Virus Challenge

Author:

Carroll Timothy D12,Jegaskanda Sinthujan3,Matzinger Shannon R12,Fritts Linda12,McChesney Michael B2,Kent Stephen J345,Fairman Jeffery6,Miller Christopher J127

Affiliation:

1. Center for Comparative Medicine, University of California, Davis

2. California National Primate Research Center, University of California, Davis

3. Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Health, Central Clinical School, Monash University

4. Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity

5. Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, Australia

6. Colby Pharmaceutical Company, Menlo Park

7. Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis

Funder

Public Health Service

National Center for Research Resources

National Institute of Allergy and Infectious Diseases

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference46 articles.

1. Induction of unnatural immunity: prospects for a broadly protective universal influenza vaccine;Nabel;Nat Med,2010

2. Influenza vaccine immunology;Dormitzer;Immunol Rev,2011

3. Advances in influenza vaccination;Reperant;F1000Prime Rep,2014

4. Using the strains and getting the vaccine licensed–a vaccine manufacturer’s view;Gerdil;Dev Biol (Basel),2003

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