Clinical Application of Phage Immunoprecipitation Sequencing to Diagnose Enterovirus D68 as the Underlying Etiology in a Case of Guillain-Barré Syndrome-Reference-Cited by-同舟云学术

Clinical Application of Phage Immunoprecipitation Sequencing to Diagnose Enterovirus D68 as the Underlying Etiology in a Case of Guillain-Barré Syndrome

Published:2024-08-31 Issue: Volume: Page:
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Li Fang Fang¹^ORCID,Faber Alison²³,Caleta Jessica M⁴,Goldfarb David M¹⁵⁶,Sekirov Inna¹⁴,Prystajecky Natalie A¹⁴,Srigley Jocelyn A¹⁵⁶,Mishaal Ram²³⁶,Jassem Agatha N¹⁴

Affiliation:

1. Department of Pathology and Laboratory Medicine, University of British Columbia , Vancouver, British Columbia , Canada

2. Department of Pediatrics, University of British Columbia , Vancouver, British Columbia , Canada

3. Sunny Hill Health Centre, British Columbia Children's Hospital , Vancouver, British Columbia , Canada

4. Public Health Laboratory, British Columbia Centre for Disease Control , Vancouver, British Columbia , Canada

5. Department of Pathology and Laboratory Medicine, British Columbia Children's and Women's Hospitals , Vancouver, British Columbia , Canada

6. British Columbia Children's Hospital Research Institute, University of British Columbia , Vancouver, British Columbia , Canada

Abstract

Abstract Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy often preceded by respiratory or gastrointestinal infections, though molecular testing of cerebrospinal fluid is often inconclusive. In a recent case of severe pediatric GBS in British Columbia, Canada, we detected cerebrospinal fluid antibodies against enterovirus D to link GBS with prior enterovirus D68 respiratory infection.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiae411/59044217/jiae411.pdf

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