Effectiveness of mRNA COVID-19 Monovalent and Bivalent Vaccine Booster Doses Against Omicron Severe Outcomes Among Adults Aged ≥50 Years in Ontario, Canada: A Canadian Immunization Research Network Study-Reference-Cited by-同舟云学术

Effectiveness of mRNA COVID-19 Monovalent and Bivalent Vaccine Booster Doses Against Omicron Severe Outcomes Among Adults Aged ≥50 Years in Ontario, Canada: A Canadian Immunization Research Network Study

Published:2023-10-05 Issue: Volume: Page:
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Grewal Ramandip¹²³,Buchan Sarah A¹²³⁴^ORCID,Nguyen Lena⁴,Nasreen Sharifa²⁴^ORCID,Austin Peter C⁴⁵,Brown Kevin A¹²⁴,Gubbay Jonathan¹⁶,Lee Nelson²,Schwartz Kevin L¹²⁴,Tadrous Mina⁴⁷⁸,Wilson Kumanan⁹¹⁰¹¹,Wilson Sarah E¹²³⁴,Kwong Jeffrey C¹²³⁴¹²¹³^ORCID

Affiliation:

1. Public Health Ontario , Toronto

2. Dalla Lana School of Public Health, University of Toronto

3. Centre for Vaccine Preventable Diseases, University of Toronto

4. ICES , Toronto

5. Institute of Health Policy, Management and Evaluation, University of Toronto

6. Department of Pathology and Laboratory Medicine, British Columbia Children's and Women's Health Centre , Vancouver

7. Institute for Health System Solutions and Virtual Care, Women's College Hospital , Toronto

8. Leslie Dan Faculty of Pharmacy, University of Toronto

9. Department of Medicine, University of Ottawa

10. Clinical Epidemiology Program, Ottawa Hospital Research Institute

11. Bruyere Research Institute , Ottawa

12. Department of Family and Community Medicine, University of Toronto

13. Toronto Western Family Health Team, University Health Network , Toronto

Abstract

Abstract We estimated the effectiveness of booster doses of monovalent and bivalent mRNA COVID-19 vaccines against Omicron-associated severe outcomes among adults aged ≥50 years in Ontario, Canada. Monovalent and bivalent mRNA COVID-19 booster doses provided similar strong initial protection against severe outcomes. Uncertainty remains around waning of protection from these vaccines.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiad419/52190600/jiad419.pdf

Reference13 articles.

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