A Single-Nucleotide Polymorphism in CYP2B6 Leads to >3-Fold Increases in Efavirenz Concentrations in Plasma and Hair Among HIV-Infected Women

Author:

Gandhi Monica1,Greenblatt Ruth M.123,Bacchetti Peter3,Jin Chengshi3,Huang Yong2,Anastos Kathryn4,Cohen Mardge56,DeHovitz Jack A.7,Sharp Gerald B.8,Gange Stephen J.9,Liu Chenglong10,Hanson Susan C.11,Aouizerat Bradley1112,

Affiliation:

1. Department of Medicine

2. Department of Clinical Pharmacy

3. Department of Epidemiology and Biostatistics, University of California, San Francisco (UCSF)

4. Department of Medicine, Albert Einstein University, Bronx

5. Department of Medicine, Stroger Hospital

6. Department of Medicine , Rush University, Chicago, Illinois

7. Department of Medicine, SUNY Downstate Medical Center, Brooklyn, New York

8. National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda

9. Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland

10. Department of Medicine, Georgetown University Medical Center, Washington, D. C

11. Department of Physiological Nursing

12. Institute for Human Genetics, University of California, San Francisco

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

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