Cell-Associated Simian Immunodeficiency Virus Accelerates Initial Virus Spread and CD4+ T-Cell Depletion in the Intestinal Mucosa
Author:
Affiliation:
1. Department of Gastroenterology, Infectious Diseases, and Rheumatology
2. Institute of Medical Virology, Charité-Universitätsmedizin Berlin, Berlin
3. German Primate Center, Göttingen, Germany
Funder
Deutsche Forschungsgemeinschaft
Otto Kuhn Stiftung
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Immunology and Allergy
Link
http://academic.oup.com/jid/article-pdf/217/9/1421/24593578/jiy055.pdf
Reference15 articles.
1. Mucosal challenge with cell-associated or cell-free feline immunodeficiency virus induces rapid and distinctly different patterns of phenotypic change in the mucosal and systemic immune systems;Howard;Immunology,2007
2. Rapid mucosal CD4(+) T-cell depletion and enteropathy in simian immunodeficiency virus-infected rhesus macaques;Kewenig;Gastroenterology,1999
3. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract;Mehandru;J Exp Med,2004
4. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract;Brenchley;J Exp Med,2004
5. Migration patterns of nonspecifically activated versus nonactivated nonhuman primate T lymphocytes: preferential homing of activated autologous CD8+ T cells in the rectal mucosa;Allers;J Immunother,2008
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Gut Microbiome Homeostasis and the CD4 T- Follicular Helper Cell IgA Axis in Human Immunodeficiency Virus Infection;Frontiers in Immunology;2021-03-19
2. The colonic mucosa-associated microbiome in SIV infection: shift towards Bacteroidetes coincides with mucosal CD4+ T cell depletion and enterocyte damage;Scientific Reports;2020-07-02
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