Effect of HIV on the Frequency and Number of Mycobacterium tuberculosis–Specific CD4+ T Cells in Blood and Airways During Latent M. tuberculosis Infection

Author:

Bunjun Rubina12,Riou Catherine12,Soares Andreia P12,Thawer Narjis12,Müller Tracey L12,Kiravu Agano12,Ginbot Zekarias12,Oni Tolu134,Goliath Rene13,Kalsdorf Barbara5,von Groote-Bidlingmaier Florian6,Hanekom Willem1,Walzl Gerhard789,Wilkinson Robert J131011,Burgers Wendy A12

Affiliation:

1. Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa

2. Division of Medical Virology, Department of Pathology, University of Cape Town, Cape Town, South Africa

3. Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Cape Town, South Africa

4. Division of Public Health Medicine, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa

5. Division of Clinical Infectious Diseases, Research Center Borstel, Germany

6. Division of Pulmonology, South Africa Department of Science and Technology–National Research Foundation, Cape Town, South Africa

7. Centre of Excellence for Biomedical Tuberculosis Research, South Africa Department of Science and Technology–National Research Foundation, Cape Town, South Africa

8. Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

9. South African Medical Research Council Centre for Tuberculosis Research, Cape Town, South Africa

10. Francis Crick Institute, London, United Kingdom

11. Department of Medicine, Imperial College London, London, United Kingdom

Funder

European and Developing Countries Clinical Trials Partnership

Wellcome Trust

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference43 articles.

1. Significant variation in presentation of pulmonary tuberculosis across a high resolution of CD4 strata;Chamie;Int J Tuberc Lung Dis,2010

2. Tuberculosis should not be considered an AIDS-defining illness in areas with a high tuberculosis prevalence;Badri;Int J Tuberc Lung Dis,2002

3. Impact of human immunodeficiency virus and CD4 count on tuberculosis diagnosis: analysis of city-wide data from Cape Town, South Africa;Gupta;Int J Tuberc Lung Dis,2013

4. How soon after infection with HIV does the risk of tuberculosis start to increase? A retrospective cohort study in South African gold miners;Sonnenberg;J Infect Dis,2005

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