Serial Vaccination and the Antigenic Distance Hypothesis: Effects on Influenza Vaccine Effectiveness During A(H3N2) Epidemics in Canada, 2010–2011 to 2014–2015

Author:

Skowronski Danuta M.12,Chambers Catharine1,De Serres Gaston345,Sabaiduc Suzana6,Winter Anne-Luise7,Dickinson James A.8,Gubbay Jonathan B.910,Fonseca Kevin1112,Drews Steven J.1314,Charest Hugues1516,Martineau Christine15,Krajden Mel617,Petric Martin17,Bastien Nathalie18,Li Yan18,Smith Derek J.19

Affiliation:

1. Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control, Vancouver,

2. School of Population and Public Health, University of British Columbia, Vancouver,

3. Direction of Biological and Occupational Risks, Institut national de santé publique du Québec,

4. Department of Social and Preventive Medicine, Laval University, Québec,

5. Infection and Immunity, Centre Hospitalier Universitaire de Québec Research Centre,

6. British Columbia Centre for Disease Control Public Health Laboratory, Vancouver,

7. Communicable Diseases, Emergency Preparedness and Response, Public Health Ontario, Toronto,

8. Departments of Family Medicine and Community Health Sciences, University of Calgary,

9. Public Health Ontario Laboratory, Public Health Ontario, Toronto,

10. Departments of Laboratory Medicine and Pathobiology and Paediatrics, University of Toronto,

11. Diagnostic Virology, Alberta Provincial Laboratory, Calgary,

12. Department of Microbiology, Immunology and Infectious Diseases, University of Calgary,

13. Diagnostic Virology, Alberta Provincial Laboratory, Edmonton,

14. Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton,

15. Laboratoire de santé publique du Québec, Institut national de santé publique du Québec,

16. Département de microbiologie, d’infectiologie et d’immunologie, l’Université de Montréal,

17. Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver,

18. Infectious Disease Prevention and Control Branch, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada; and

19. Department of Zoology, University of Cambridge, England

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Canadian Institutes of Health Research

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

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