Implementing a Multisite Clinical Trial in the Midst of an Ebola Outbreak: Lessons Learned From the Sierra Leone Trial to Introduce a Vaccine Against Ebola

Author:

Carter Rosalind J1,Idriss Ayesha2,Widdowson Marc-Alain1,Samai Mohamed23,Schrag Stephanie J1,Legardy-Williams Jennifer K1,Estivariz Concepcion F1,Callis Amy1,Carr Wendy1,Webber Winston2,Fischer Marc E1,Hadler Stephen1,Sahr Foday2,Thompson Melvina2,Greby Stacie M1,Edem-Hotah Joseph2,Momoh Roselyn M’baindu2,McDonald Wendi1,Gee Julianne M1,Kallon Ahamed Flagbata2,Spencer-Walters Dayo4,Bresee Joseph S1,Cohn Amanda1,Hersey Sara1,Gibson Laura5,Schuchat Anne1,Seward Jane F1

Affiliation:

1. Centers for Disease Control and Prevention, Atlanta, Georgia

2. College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone

3. Ministry of Health and Sanitation, Freetown, Sierra Leone

4. E-Health Africa, Freetown, Sierra Leone

5. Conceptual Mindworks, Inc., Washington DC

Funder

Centers for Disease Control and Prevention

Biomedical Advanced Research and Development Authority

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference20 articles.

1. Implementing an Ebola Vaccine Study - Sierra Leone;Widdowson;MMWR Suppl,2016

2. The Sierra Leone Trial to Introduce a Vaccine against Ebola: an evaluation of rVSVΔG-ZEBOV vaccine tolerability and safety during the West Africa Ebola outbreak;Samai;J Infect Dis,2018

3. Ebola virus disease in health care workers — Sierra Leone, 2014;Kilmarx;MMWR,2014

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