Prevalence, Incidence, and Predictors of Kaposi Sarcoma–Associated Herpesvirus Infection Among Young Men Who Have Sex With Men in the Southern United States-Reference-Cited by-同舟云学术

Prevalence, Incidence, and Predictors of Kaposi Sarcoma–Associated Herpesvirus Infection Among Young Men Who Have Sex With Men in the Southern United States

Published:2023-09-15 Issue: Volume: Page:
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Salyards Maverick¹,Nijhawan Ank E²³,Kuo Jacky⁴,Knights Sheena M²³^ORCID,Lazarte Susana²³,Labo Nazzarena⁵,Miley Wendell⁵,Whitby Denise⁵^ORCID,Hwang Lu-Yu⁶,Kornberg Anna-William⁷,Fujimoto Kayo⁴^ORCID,Chiao Elizabeth Y⁷^ORCID

Affiliation:

1. Institute of Behavioral Research, Texas Christian University , Fort Worth

2. Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, University of Texas Southwestern

3. Parkland Health , Dallas

4. Center for Health Promotion and Prevention Research, School of Public Health, The University of Texas Health Science Center at Houston

5. Viral Oncology Section, AIDS and Cancer Virus Program, Leidos Biomedical Inc, Frederick National Laboratory for Cancer Research , Maryland

6. Center for Infectious Diseases, School of Public Health, The University of Texas Health Science Center at Houston

7. Division of Cancer Prevention, Department of Epidemiology, University of Texas MD Anderson Cancer Center , Houston

Abstract

Abstract Kaposi sarcoma (KS) continues to cause substantial morbidity and mortality in populations at risk in the southern United States. Utilizing biospecimens from the Houston site of the Young Men's Affiliate Project, 351 men who have sex with men had blood tested for KS-associated herpesvirus (KSHV) IgG. Seroprevalence, seroconversion between time points, and demographic and clinical correlates were measured. KSHV prevalence was 36.7% and incidence was 8.9 per 100 person-years. Furthermore, prevalence and incidence were higher among Black individuals, people living with HIV, and those with a history of syphilis. Further research on KSHV risk may improve health disparities in KS diagnosis and outcomes.

Funder

National Institute of Mental Health

Frederick National Laboratory for Cancer Research

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiad384/52075272/jiad384.pdf

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